My job is systems analyst a media company, but at the same time I have only had my EX485 for just over a month.
My understanding of WHS is that it is a variation of Windows Server 2003 with certain functionality removed, and a few thigns added. Most of the things removed are specific to larger businesses but some home users that work with server enviroments might miss. The added functionality is what is Drive extender, automated backups, remote access, and an attempt to setup a headless unit for home users. Because this is a server, there is also the ability to load Add-in's(extra software). The biggest thing to keep in mind with additional software is you want to ensure it is written for WHS or that you can use the network share to access storage. Not doiing so can cause issues with Drive Extender(What I have heard)
Drive Extender is in my opionion the biggest unknown. The concept behind it is simple. Instead of haveing to educate the home user on the merits and meathods of RAID, drive extender tries to provide the same level of data saftey without the potential complexitities of figuring out what raid setup you are going to run. My expectation is that in a NAS you will be running raid for redundency.
For home use I like drive extender as it will somehwat reduce the cost and potential issues with raid. Basically the only thing you have to be concerned about is making sure you tell WHS what you want duplicated for data protection and you should be good to go. There is also the potential to get allot more storage from what you buy. A real breif explination is like this.
If you buy 3 2TB Seagate drives and run Raid 5 you will only get 4 TB of storage after raid is setup. But you have zero risk of loosing data, and it will remain avaliable with one drive failur. that could be allot of storage lost if you find you really only care about maybe 500 gig of storage being protected from loss. If you just run Drive extender and don't raid the drives you only loose the storgae of duplicating what you want protected. So then you would have the capacity of all 3 drives and just loose 500 gig from the duplication on an extra drive.
One of the nice things about the EX series WHS is that the added software from HP can do some really cool stuff. With Twonky media, the itunes server and the MAC Backup for TimeMachine, there is allot of extra functionality that provides a great multimedia experience.
I believe there are some SAN devices that can do UPNP and DLNA for multimedia though. My expectation is that the biggest difference would be the ability to added additional programs and drive extender compared to raid 1 or 5(depends on how many drives) in a NAS
Mavrrick
HTPC1(Phenom 9950/8GB/HDPVR/HVR-2250)(Bedroom computer and TV with 24" Dell Ultrasharp)
HTPC2(Athlon II 7750/2GB/HVR-1800)(Serves living room TV)
MSS EX485 with Pentium Dual Core E5200(2x1.5TB,1x750GB,1x2TB)

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